Radical centrism (also called the radical center, the radical centre or the radical middle) is a concept that arose in Western nations in the late 20th century.

The radical in the term refers to a willingness on the part of most radical centrists to call for fundamental reform of institutions. The centrism refers to a belief that genuine solutions require realism and pragmatism, not just idealism and emotion. One radical centrist text defines radical centrism as "idealism without illusions", a phrase originally from John F. Kennedy. This approach typically leads to endorsing evidence, rather than ideology, as the guiding principle.

Radical centrists borrow ideas from the left and the right, often melding them together. Most support market-based solutions to social problems, with strong governmental oversight in the public interest. There is support for increased global engagement and the growth of an empowered middle class in developing countries. In the US, many radical centrists work within the major political parties, but they also support independent or third-party initiatives and candidacies.

One common criticism of radical centrism is that its policies are only marginally different from conventional centrist policies. Some observers see radical centrism as primarily a process of catalyzing dialogue and fresh thinking among polarized people and groups.